Krska, Shane: search on Z-Library

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1

The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis

Krska, Shane W., DiRocco, Daniel A., Dreher, Spencer D., Shevlin, Michael

Journal:

Accounts of Chemical Research

Year:

2017

Language:

english

File:

PDF, 4.22 MB

english, 2017

2

New Efficient Asymmetric Synthesis of Taranabant, a CB1R Inverse Agonist for the Treatment of Obesity

Wallace, Debra J., Campos, Kevin R., Shultz, C. Scott, Klapars, Artis, Zewge, Daniel, Crump, Brian R., Phenix, Brian D., McWilliams, J. Christopher, Krska, Shane, Sun, Yongkui, Chen, Cheng-yi, Spindle

Journal:

Organic Process Research & Development

Year:

2009

Language:

english

File:

PDF, 150 KB

english, 2009

3

Practical, Highly Convergent, Asymmetric Synthesis of a Selective PPARγ Modulator

Maligres, Peter E., Humphrey, Guy R., Marcoux, Jean-François, Hillier, Michael C., Zhao, Dalian, Krska, Shane, Grabowski, Edward J. J.

Journal:

Organic Process Research & Development

Year:

2009

Language:

english

File:

PDF, 227 KB

english, 2009

4

Silyl Phosphorus and Nitrogen Donor Chelates for Homogeneous Ortho Borylation Catalysis

Ghaffari, Behnaz, Preshlock, Sean M., Plattner, Donald L., Staples, Richard J., Maligres, Peter E., Krska, Shane W., Maleczka, Robert E., Smith, Milton R.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 704 KB

english, 2014

5

Correction: The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

Cernak, Tim, Dykstra, Kevin D., Tyagarajan, Sriram, Vachal, Petr, Krska, Shane W.

Journal:

Chemical Society Reviews

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

6

Highly Efficient Synthesis of β-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines

Hsiao, Yi, Rivera, Nelo R., Rosner, Thorsten, Krska, Shane W., Njolito, Eugenia, Wang, Fang, Sun, Yongkui, Armstrong, Joseph D., Grabowski, Edward J. J., Tillyer, Richard D., Spindler, Felix, Malan, C

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 40 KB

english, 2004

7

Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)

Strotman, Neil A., Baxter, Carl A., Brands, Karel M. J., Cleator, Ed, Krska, Shane W., Reamer, Robert A., Wallace, Debra J., Wright, Timothy J.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

8

Synthesis of Water-Soluble Carbosilane Dendrimers

Krska, Shane W., Seyferth, Dietmar

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 185 KB

english, 1998

9

Site-Selective Synthesis of Insulin Azides and Bioconjugates

Boga, Sobhana Babu, Krska, Shane W., Lin, Songnian, Pissarnitski, Dmitri, Yan, Lin, Kekec, Ahmet, Tang, Weijuan, Pierson, Nicholas A., Strulson, Christopher A., Streckfuss, Eric, Zhu, Xiaohong, Zhang,

Journal:

Bioconjugate Chemistry

Year:

2019

File:

PDF, 1.39 MB

2019

10

High-Throughput Optimization of Ir-Catalyzed C–H Borylation: A Tutorial for Practical Applications

Preshlock, Sean M., Ghaffari, Behnaz, Maligres, Peter E., Krska, Shane W., Maleczka, Robert E., Smith, Milton R.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 3.00 MB

english, 2013

11

CO Cross-Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols

Peter E. Maligres, Jing Li, Shane W. Krska, John D. Schreier, Izzat T. Raheem

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 836 KB

english, 2012

12

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

Cernak, Tim, Dykstra, Kevin D., Tyagarajan, Sriram, Vachal, Petr, Krska, Shane W.

Journal:

Chemical Society Reviews

Year:

2015

Language:

english

File:

PDF, 10.32 MB

english, 2015

13

Carboamination: Additions of Imine CN Bonds Across Alkynes Catalyzed by Imidozirconium Complexes

Rebecca T. Ruck, Rebecca L. Zuckerman, Shane W. Krska, Robert G. Bergman

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

14

Protecting Group Free Radical C-H Trifluoromethylation of Peptides

Ichiishi, Naoko, Caldwell, John, Lin, Melissa, Zhong, Wendy, Zhu, Xiaohong, Streckfuss, Eric C., Kim, Hai-Young, Parish, Craig A., Krska, Shane

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018

15

Enantioselective synthesis of a chiral fluoropiperidine via asymmetric hydrogenation of a vinyl fluoride

Shane W. Krska, Jeffrey V. Mitten, Peter G. Dormer, Dale Mowrey, Fouzia Machrouhi, Yongkui Sun, Todd D. Nelson

Journal:

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

16

Deactivation of Heterogeneous Hydrogenation Catalysts by Alcoholic Solvents

Singh, Utpal K., Krska, Shane W., Sun, Yongkui

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 280 KB

english, 2006

17

Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst

Chang, Mingxin, Huang, Yuhua, Liu, Shaodong, Chen, Yonggang, Krska, Shane W., Davies, Ian W., Zhang, Xumu

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 720 KB

english, 2014

18

ChemInform Abstract: Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst.

Chang, Mingxin, Huang, Yuhua, Liu, Shaodong, Chen, Yonggang, Krska, Shane W., Davies, Ian W., Zhang, Xumu

Journal:

Year:

2015

File:

PDF, 27 KB

2015

19

Enabling Efficient Late Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction Driven Data Processing

Yao, Huifang, Liu, Yong, Tyagarajan, Sriram, Streckfuss, Eric, Reibarkh, Mikhail, Chen, Kuanchang, Zamora, Ismael, Fontaine, Fabien, Goracci, Laura, Helmy, Roy, Bateman, Kevin P., Krska, Shane William

Journal:

European Journal of Organic Chemistry

Year:

2017

Language:

english

File:

PDF, 2.95 MB

english, 2017

20

Carboamination: Additions of Imine CN Bonds Across Alkynes Catalyzed by Imidozirconium Complexes

Rebecca T. Ruck, Rebecca L. Zuckerman, Shane W. Krska, Robert G. Bergman

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

21

ChemInform Abstract: Silyl Phosphorus and Nitrogen Donor Chelates for Homogeneous ortho Borylation Catalysis.

Ghaffari, Behnaz, Preshlock, Sean M., Plattner, Donald L., Staples, Richard J., Maligres, Peter E., Krska, Shane W., Maleczka, Robert E. Jr., Smith, Milton R. III

Journal:

Year:

2015

File:

PDF, 22 KB

2015

22

On the stability of the π-allyl intermediate in molybdenum-catalyzed asymmetric alkylations

Jennifer A.R. Luft, Zhi-Xiang Yu, David L. Hughes, Guy C. Lloyd-Jones, Shane W. Krska, Kendall N. Houk

Journal:

Tetrahedron: Asymmetry

Year:

2006

Language:

english

File:

PDF, 394 KB

english, 2006

23

Reducing Limitation in Probe Design: The Development of a Diazirine-Compatible Suzuki–Miyaura Cross Coupling Reaction

Ichiishi, Naoko, Moore, Keith P., Wassermann, Anne Mai, Wolkenberg, Scott E., Krska, Shane W.

Journal:

ACS Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 1.65 MB

english, 2018

24

Highly Efficient Asymmetric Synthesis of Sitagliptin

Hansen, Karl B., Hsiao, Yi, Xu, Feng, Rivera, Nelo, Clausen, Andrew, Kubryk, Michele, Krska, Shane, Rosner, Thorsten, Simmons, Bryon, Balsells, Jaume, Ikemoto, Nori, Sun, Yongkui, Spindler, Felix, Mal

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 963 KB

english, 2009

25

Synthesis of a Tertiary Carbinamide via a Novel Rh-Catalyzed Asymmetric Hydrogenation

Limanto, John, Shultz, C. Scott, Dorner, Benjamin, Desmond, Richard A., Devine, Paul N., Krska, Shane W.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

26

Understanding the Origin of Unusual Stepwise Hydrogenation Kinetics in the Synthesis of the 3-(4-Fluorophenyl)morpholine Moiety of NK 1 Receptor Antagonist Aprepitant

Brands, Karel M. J., Krska, Shane W., Rosner, Thorsten, Conrad, Karen M., Corley, Edward G., Kaba, Mahmoud, Larsen, Robert D., Reamer, Robert A., Sun, Yongkui, Tsay, Fuh-Rong

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

27

Heterocyclic Regioisomer Enumeration (HREMS): A Cheminformatics Design Tool

Tyagarajan, Sriram, Lowden, Christopher T., Peng, Zhengwei, Dykstra, Kevin D., Sherer, Edward C., Krska, Shane W.

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 852 KB

english, 2015

28

ChemInform Abstract: Dynamic Kinetic Resolution: Asymmetric Transfer Hydrogenation of α-Alkyl-Substituted β-Ketoamides.

John Limanto, Shane W. Krska, Benjamin T. Dorner, Enrique Vazquez, Naoki Yoshikawa, Lushi Tan

Journal:

Year:

2010

File:

PDF, 38 KB

2010

29

Reversible CH activation of an N-methyl group in a bis-Zr(IV) diazametallacycle: generation of an end-on, side-on coordinated bridging alkylideneamido ligand

Rebecca L. Zuckerman, Shane W. Krska, Robert G. Bergman

Journal:

Journal of Organometallic Chemistry

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

30

Reversed-Polarity Synthesis of Diaryl Ketones via Palladium-Catalyzed Cross-Coupling of Acylsilanes

Schmink, Jason R., Krska, Shane W.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 856 KB

english, 2011

31

Enantioselective Hydrogenation of α-Aryloxy α,β-Unsaturated Acids. Asymmetric Synthesis of α-Aryloxycarboxylic Acids

Maligres, Peter E., Krska, Shane W., Humphrey, Guy R.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

32

Mechanistic Studies of Molybdenum-Catalyzed Asymmetric Alkylation

David L. Hughes, Shane W. Krska, Robert A. Reamer, David J. Mathre, Yongkui Sun

Journal:

Year:

2005

File:

PDF, 8 KB

2005

33

Unlocking the Potential of Asymmetric Hydrogenation at Merck

Shultz, C. Scott, Krska, Shane W.

Journal:

Accounts of Chemical Research

Year:

2007

Language:

english

File:

PDF, 526 KB

english, 2007

34

Synthesis of Antifungal Glucan Synthase Inhibitors from Enfumafungin

Zhong, Yong-Li, Gauthier, Donald R., Shi, Yao-Jun, McLaughlin, Mark, Chung, John Y. L., Dagneau, Philippe, Marcune, Benjamin, Krska, Shane W., Ball, Richard G., Reamer, Robert A., Yasuda, Nobuyoshi

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

35

Copper-catalysed benzylic CâH coupling with alcohols via radical relay enabled by redox buffering

Hu, Huayou, Chen, Si-Jie, Mandal, Mukunda, Pratik, Saied Md, Buss, Joshua A., Krska, Shane W., Cramer, Christopher J., Stahl, Shannon S.

Journal:

Nature Catalysis

Year:

2020

Language:

english

File:

PDF, 1.40 MB

english, 2020

36

Designed Ligands as Probes for the Catalytic Binding Mode in Mo-Catalyzed Asymmetric Allylic Alkylation

Barry M. Trost, Kalindi Dogra, Iwao Hachiya, Takashi Emura, David L. Hughes, Shane Krska, Robert A. Reamer, Michael Palucki, Nobuyoshi Yasuda, Paul J. Reider

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

37

A Soluble Copper(I) Source and Stable Salts of Volatile Ligands for Copper-Catalyzed C–X Couplings

Maligres, Peter E., Krska, Shane W., Dormer, Peter G.

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

38

A Traceless Directing Group for CH Borylation

Preshlock, Sean M., Plattner, Donald L., Maligres, Peter E., Krska, Shane W., Maleczka, Robert E., Smith, Milton R.

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

39

Catalytic Asymmetric Synthesis of an HIV Integrase Inhibitor

Zhong, Yong-Li, Krska, Shane W., Zhou, Hua, Reamer, Robert A., Lee, Jaemoon, Sun, Yongkui, Askin, David

Journal:

Organic Letters

Year:

2009

Language:

english

File:

PDF, 202 KB

english, 2009

40

Cu-Mediated C–H 18 F-Fluorination of Electron-Rich (Hetero)arenes

McCammant, Matthew S., Thompson, Stephen, Brooks, Allen F., Krska, Shane W., Scott, Peter J. H., Sanford, Melanie S.

Journal:

Organic Letters

Year:

2017

Language:

english

File:

PDF, 1.11 MB

english, 2017

41

Use of Steric Hindrance and a Metallacyclobutene Resting State to Develop Robust and Kinetically Characterizable Zirconium-Based Imine Metathesis Catalysts

Krska, Shane W., Zuckerman, Rebecca L., Bergman, Robert G.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 123 KB

english, 1998

42

Conclusive Evidence for a Retention−Retention Pathway for the Molybdenum-Catalyzed Asymmetric Alkylation

Lloyd-Jones, Guy C., Krska, Shane W., Hughes, David L., Gouriou, Laure, Bonnet, Veronique D., Jack, Kevin, Sun, Yongkui, Reamer, Robert A.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 53 KB

english, 2004

43

Enantioselective Synthesis of an HCV NS5a Antagonist

Mangion, Ian K., Chen, Cheng-yi, Li, Hongmei, Maligres, Peter, Chen, Yonggang, Christensen, Melodie, Cohen, Ryan, Jeon, Ingyu, Klapars, Artis, Krska, Shane, Nguyen, Hoa, Reamer, Robert A., Sherry, Ben

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 536 KB

english, 2014

44

ChemInform Abstract: Cobalt Precursors for High-Throughput Discovery of Base Metal Asymmetric Alkene Hydrogenation Catalysts.

Friedfeld, Max R., Shevlin, Michael, Hoyt, Jordan M., Krska, Shane W., Tudge, Matthew T., Chirik, Paul J.

Journal:

Year:

2014

File:

PDF, 37 KB

2014

45

ChemInform Abstract: A Traceless Directing Group for C-H Borylation.

Preshlock, Sean M., Plattner, Donald L., Maligres, Peter E., Krska, Shane W., Maleczka, Robert E. Jr., Smith, Milton R. III

Journal:

Year:

2014

File:

PDF, 40 KB

2014

46

Dynamic Kinetic Resolution: Asymmetric Transfer Hydrogenation of α-Alkyl-Substituted β-Ketoamides

Limanto, John, Krska, Shane W., Dorner, Benjamin T., Vazquez, Enrique, Yoshikawa, Naoki, Tan, Lushi

Journal:

Organic Letters

Year:

2010

Language:

english

File:

PDF, 190 KB

english, 2010

47

Anionic Cyclopolymerization of Linked Bis(vinylsilyl) Monomers: Substituent Control over Polymer Structure

Krska, Shane W., Ueno, Keiji, Seyferth, Dietmar

Journal:

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

48

Late-Stage Functionalization of Biologically Active Heterocycles Through Photoredox Catalysis

DiRocco, Daniel A., Dykstra, Kevin, Krska, Shane, Vachal, Petr, Conway, Donald V., Tudge, Matthew

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

49

Site-Selective Synthesis of Insulin Azides and Bioconjugates

Boga, Sobhana Babu, Krska, Shane W., Lin, Songnian, Pissarnitski, Dmitri, Yan, Lin, Kekec, Ahmet, Tang, Weijuan, Pierson, Nicholas A., Strulson, Christopher A., Streckfuss, Eric, Zhu, Xiaohong, Zhang,

Journal:

Bioconjugate Chemistry

Year:

2019

Language:

english

File:

PDF, 1.39 MB

english, 2019

50

Enantioselective Hydrogenation of α-Aryloxy α,β-Unsaturated Acids. Asymmetric Synthesis of α-Aryloxycarboxylic Acids.

Peter E. Maligres, Shane W. Krska, Guy R. Humphrey

Journal:

Year:

2004

File:

PDF, 31 KB

2004

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